Erectile dysfunction drugs.

Nov. 16, 2005 — A drug called Revatio may help treat an erectile dysfunction drugs
condition called pulmonary arterial hypertension.

Patients with pulmonary hypertension have elevated blood pressure in the pulmonary (lung) blood vessels. The condition often arises from lung problems, but some cases are without a known cause. It can result in heart failure and early death.

Unfortunately, most of the herbal cure for erectile dysfunction that are used to treat this serious condition are not easy to take and are given by IV, injection, or inhalation — with real risks of unwanted side effects.

Revatio has the same active ingredient — sildenafil — as Viagra. Revatio and Viagra are made by Pfizer.

Pfizer funded the new study, which appears in The New England Journal of Medicine. Pfizer is a WebMD sponsor.

The researchers included Nazzarene Galie, MD, of the cardiology institute at Italy’s University of Bologna.

Walking Test

The study lasted for 12 weeks. It included 278 patients with pulmonary hypertension. The patients lived in the U.S., Mexico, South America, Europe, Asia, Australia, South Africa, and Israel.

Three times daily, the patients took Revatio (20, 40, or 80 milligrams) or an empty drug (placebo) orally. That was in addition to any other standard pulmonary hypertension medications.

The big question was how far patients could walk in six minutes. That’s an important exercise test for patients with pulmonary hypertension. The farther patients can walk, the better.

Walking Farther

All of the patients taking Revatio walked farther at the end of the study:

• 20Viagra sample pack
  group: Walked about 148 extra feet (a 13% increase).
• 40-milligram group: Walked about 151 extra feet (a 13% increase).
• 80-milligram group: Walked about 164 extra feet (nearly a 15% increase).

Higher doses didn’t bring a notable increase in distance walked, the researchers report.

Patients were then allowed to take Revatio for up to a year; 230 did so. The researchers looked at the walking tests of 222 of those who were only taking Revatio as treatment. After a year, they walked about 167 extra feet, on average, compared with the beginning of the study.

How Patients Fared

Most of the patients included in the study had milder stages of pulmonary hypertension. Few cases worsened, regardless of treatment type, the study shows.

Patients taking Revatio weren’t any more or less likely to have their symptoms worsen during the trial.

The study wasn’t designed to see if Revatio helped patients live longer. Four died during the study. No deaths were judged to be linked to the generic erectile dysfunction drug, write the researchers.

Side effects seen with Revatio were mild or moderate and included headache, flushing, muscle pain, and diarrhea, report Galie and colleagues.

July 24, 2006 — Like Viagra before it, a drug once studied to treat heart problems may help treat sexual dysfunction. But this time it’s being tested exclusively for women.

A new study shows that a modified version of the generic erectile dysfunction drugs
heart drug Candoxatril was effective at increasing blood flow to the vagina in animal tests.

If further research confirms these results in humans, the drug may be used to treat female sexual arousal disorder (FSAD).

Researchers say an estimated 40% of women suffer from FSAD or other forms of sexual dysfuction, such as low libido or pain during intercourse.

Candoxatril went into clinical trials in the 1990s as a heart failureheart failure medication but has since become the focus of efforts to develop a medication to treat female sexual arousal disorder.

How the Drug Works

Candoxatril is one of several compounds that targets levels of levitra vs cialis
intestinal peptide (VIP), which controls blood flow to the vagina. Researchers say decreased blood flow to the vagina is thought to be a key factor in female sexual arousal disorder.

An enzyme called NEP degrades VIP in the body, and Candoxatril works by blocking NEP.

In a new study, published in the Journal of Medicinal Chemistry, researchers altered the molecular structure of Candoxatril in order to focus the drug to treat female sexual arousal dysfunction.

In animal tests, researchers at Pfizer Global Research and Citrate generic sildenafil viagra
in the U.K., found the new compound online sale viagra
blocked NEP, took effect quickly, and the effect lasted for a ed meds
short time.

They say the results suggest that the drug might have similar effects in humans, but further research is needed.

Nov. 7, 2005 - The drug made famous for its treatment of erectile dysfunction appears to have another therapeutic use.

A study in the journal Erectile dysfunction drugs suggests Viagra could help treat a circulatory disorder called Raynaud’s phenomenon, which affects about 5% of the population. Raynaud’s phenomenon can be associated with other diseases such as lupus.

Raynaud’s phenomenon causes episodes of numbness, tingling, and pain in the fingers and toes, as well as skin sores or gangrene in severe cases. The attacks are spawned by spasms in small blood vessels in response to cold erectile dysfunction medicine
or emotional stress.

These spasms cause blood vessels to constrict and compromise blood flow to distal areas such as toes and fingers. The disorder is sometimes treated with medications to relax the blood vessels, but this is not always successful.

The Viagra study involved 18 patients (mostly women) whose Raynaud’s symptoms were not responsive to conventional therapies. While taking Viagra twice a day for four weeks, the patients drug for treatment of erectile dysfunction improved blood flow in the capillaries and fewer Raynaud’s attacks. Symptoms improved and the duration of attacks was also shorter. In those who had skin sores, the ulcers began to heal visibly.

These effects did not occur while patients were taking a placebo. At the end of the study, 16 of the participants asked to continue taking Viagra off-label (that is, for a purpose other than its Over the counter erectile dysfunction drug
use).

Viagra causes blood vessels to dilate in a different way from other vasodilating drugs, which may explain why it helped Raynaud’s patients who didn’t respond to standard treatments. The erectile dysfunction pills
conclude that drugs like Viagra could offer “a promising new approach in patients with microcirculatory disorders.”

Although Viagra has risk for serious side effects such as heart attack, stroke, and vision loss, none of the study participants reported any such adverse effect. The side effects reported by study participants included headache, muscle pain, flushing, mild nausea, dizziness, and nasal congestion.

One of the researchers has served as a consultant and speaker for Viagra’s manufacturer, Pfizer. Pfizer is a WebMD sponsor.

By Sheryl Ubelacker Health Reporter, The Canadian Press

Sildenafil citrate soft tab

TORONTO - They’re embedded in everything from mattresses to insoles for shoes to wrist bands - but there is no definitive scientific evidence that static magnets actually relieve chronic pain, researchers say.

Products that incorporate static magnets are a multibillion-dollar business worldwide and many chronic pain sufferers are drawn to the promise they hold for alleviating such nagging conditions as arthritis, fibromyalgia and low back discomfort.

The theory from proponents is that the device’s magnetic field increases blood flow, causing increased oxygen, nutrients, hormones and painkilling endorphins to be distributed to tissues in the affected area.

So researchers at the Ed tablets
Medicine, Peninsula Medical School, at the Universities of Exeter and Plymouth decided to search the medical literature to determine whether there is any proof magnets can actually reduce pain.

In their analysis of nine randomized trials comparing products containing magnets with those containing either no magnet or very weak ones, the researchers found that the data did not support the use of the alternative therapy for pain control.

“There is no definite grounds of being absolutely sure that a magnet works or not,” lead author Dr. Max Pittler, a complementary medicine specialist, said Monday from Exeter, England.

“The evidence does not support the use of static magnets for pain relief and therefore magnets cannot be recommended as an effective treatment,” he said. The analysis is published in Tuesday’s Canadian Medical Association Journal.

However, Pittler acknowledged that the findings also mean that magnets could work - but the clinical trials weren’t able to prove that either. In part, that’s because pain measurements are subjective - subjects self-report pain levels - and individual studies in the analysis may have been too small to provide statistically relevant results.

Still, Pittler said the biggest concern is that people seeking to ease their pain may be buying into - and paying big bucks - for a therapy that may not be effective.

“It is important to realize that this is a situation where there is a huge market out there,” he said. “In a situation where you don’t have rigorous data . . . patients are putting their hopes into a magnet and spending a lot of money on it.”

He suggests many pain sufferers would be better off taking an erectile pill
painkiller such as ASA or acetaminophen.

“Or if patients are keen on trying complementary medicine for certain pain conditions, there is some data available that acupuncture might alleviate some of the pain they feel,” Pittler said. “Acupuncture might be one complementary therapy in certain pain conditions,” such as osteoarthritis.

Health Canada considers claims for specific therapeutic benefits of static magnets to be unfounded, a spokeswoman for the federal department said by e-mail Monday. “These claims include, but are not limited to: pain relief, increased blood circulation, increased oxygenation, reduction of high blood pressure, stimulation of the immune system and the treatment of sleep disorders, infections, depression, erectile dysfunction, rheumatoid disease and cancer.”

A static magnet promoted for any of these purposes is considered a violation of the Food and Drugs Act or Medical Devices Regulations.

Commenting on the analysis, naturopath Kieran Cooley agreed that magnets wouldn’t be high on the list of possible therapies to treat chronic pain.

“I don’t think naturopaths overall would be strong advocates of magnetic therapy if (patients) hadn’t already tried other modalities like acupuncture or other pain-specific treatments for what they’re going through, whether it’s fibromyalgia, chronic fatigue syndrome or even acute back pain,” said Cooley, a researcher and assistant professor at the Canadian College of Online sildenafil citrate Medicine in Toronto.

“Acupuncture is probably the biggest one. Mild to moderate exercise has actually been shown to have the best effect on pain overall of any sort of therapy you can use, even conventional drugs or over-the-counter pain medications like Advil or Aspirin.”

Yet magnets can’t be written off completely until more definitive evidence on their erectile dysfunction tabs
or lack of effectiveness is obtained, Cooley conceded. “There are clearly some people (in the British analysis) who are benefiting from the therapy. There are other people who are not benefiting very much and a few people who seem to be getting worse.”

“So in that respect, magnet therapy is definitely a buyer-beware or consumer-beware kind of industry.”

The following recalls have been announced:

• TWC Global of Mountain View, Calif., is recalling 200 boxes of its supplement products sold under the names Axcil and Desirin because the products contain potentially harmful, undeclared ingredients. No illnesses have been reported, according to the company. The products, manufactured in the U.S. and sold on the Internet nationwide, are sold as a 15-capsule blister-pack, packaged in a box.

The company said in a statement Wednesday that the Food and Drug Administration found samples of the products contained an active ingredient for an FDA-approved drug for erectile dysfunction. The undeclared chemicals pose a threat to consumers because they may interact with nitrates found in some prescription drugs and may lower blood pressure to dangerous levels, the company said.

Customers should stop using the products blindness causing citrate sildenafil and contact their doctor if they have experienced any problems that may be related to taking this product. Any reactions should be reported to the Food and Drug Administration’s MedWatch adverse event reporting program at http://www.fda.gov/medwatch/report.htm. For more information, consumers can call the company at 650-575-0828.

• Bravo! LCC is recalling tubes of frozen cat and dog food, because of a potential bacterial erectile dysfunction medication
. The recall includes various-sized tubes of Bravo Original Formula Chicken Blend frozen raw food and 2-pound tubes of Bravo Basic Formula Finely Ground Chicken frozen raw food, because they could be contaminated with both salmonella and Listeria monocytogenes. The original formula chicken was manufactured on August 24 and the finely ground chicken was manufactured on August 14. The company is also recalling various-sized tubes of Bravo Original Formula Turkey Blend frozen raw food because they could be contaminated with listeria. This product was manufactured on August 24.

Both salmonella and listeria can cause serious infections in cats, dogs and — if there is erectile pill
— in young children, frail or elderly people and others with weakened immune systems. The company has received no reports of illness in people or animals. Details: by phone at 866-922-9222; by Web at http://www.bravorawdiet.com

By Sheryl Ubelacker Health Reporter, The Canadian Press

TORONTO - They’re embedded in everything from mattresses to insoles for shoes to wrist bands - but there is no definitive scientific evidence that static magnets actually relieve chronic pain, researchers say.

Products that incorporate static magnets are a multibillion-dollar business worldwide and many chronic pain sufferers are drawn to the promise they hold for alleviating such nagging conditions as arthritis, fibromyalgia and low back discomfort.

The theory from proponents is that the device’s magnetic field increases blood flow, causing increased oxygen, nutrients, hormones and painkilling endorphins to be distributed to tissues in the affected area.

So researchers at the Generic say viagra wordpress
Medicine, Peninsula Medical School, at the Universities of Exeter and Plymouth decided to search the medical literature to determine whether there is any proof magnets can actually reduce pain.

In their analysis of nine randomized trials comparing products containing magnets with those containing either no magnet or very weak ones, the researchers found that the data did not support the use of the alternative therapy for pain control.

“There is no definite grounds of being absolutely sure that a magnet works or not,” lead author Dr. Max Pittler, a complementary medicine specialist, said Monday from Exeter, England.

“The evidence does not support the use of static magnets for pain relief and therefore magnets cannot be recommended as an effective treatment,” he said. The analysis is published in Tuesday’s Canadian Medical Association Journal.

However, Pittler acknowledged that the findings also mean that magnets could work - but the clinical trials weren’t able to prove that either. In part, that’s because pain measurements are subjective - subjects self-report pain levels - and individual studies in the analysis may have been too small to provide generic research viagra
relevant results.

Still, Pittler said the biggest concern is that people seeking to ease their pain may be buying into - and paying big bucks - for a therapy that may not be effective.

“It is important to realize that this is a situation where there is a huge market out there,” he said. “In a situation where you don’t have rigorous data . . . patients are putting their hopes into a magnet and spending a lot of money on it.”

He suggests many pain sufferers would be better off taking an over-the-counter painkiller such as ASA or acetaminophen.

“Or if patients are keen on trying complementary medicine for certain pain conditions, there is some data available that acupuncture might alleviate some of the pain they feel,” Pittler said. “Acupuncture might be one complementary therapy in certain pain conditions,” such as osteoarthritis.

Health Canada considers claims for specific therapeutic benefits of static magnets to be unfounded, a spokeswoman for the federal department said by e-mail Monday. “These claims include, but are not limited to: pain relief, increased blood circulation, increased oxygenation, reduction of high blood pressure, stimulation of the immune system and the treatment of sleep disorders, infections, depression, erectile dysfunction, rheumatoid disease and cancer.”

A static magnet promoted for any of these purposes is considered a violation of the Food and Drugs Act or Medical Devices Regulations.

Commenting on the analysis, naturopath Kieran Cooley agreed that magnets wouldn’t be high on the list of possible therapies to treat chronic pain.

“I don’t think naturopaths overall would be strong advocates of magnetic therapy if (patients) hadn’t already tried other modalities like acupuncture or other pain-specific treatments for what they’re going through, whether it’s fibromyalgia, chronic fatigue syndrome or even acute back pain,” said Cooley, a researcher and assistant professor at the Canadian College of Naturopathic Medicine in Toronto.

“Acupuncture is probably the biggest one. Mild to moderate exercise has actually been shown to have the best effect on pain overall of any sort of therapy you can use, even conventional drugs or over-the-counter pain medications like Advil or Aspirin.”

Yet magnets can’t be written off completely until more definitive evidence on their effectiveness or lack of effectiveness is obtained, Cooley conceded. “There are clearly some people (in the British analysis) who are benefiting from the therapy. There are other people who are not benefiting very much and a few people who seem to be getting worse.”

“So in that respect, magnet therapy is definitely a buyer-beware or consumer-beware kind of industry.”